You know, I can't help but think the lack of Wi-fi is going to hurt its sales...
Granted, the lack of Wi-Fi is a downer to some, but I doubt it would actually hurt sales. After all, obviously, this is game is targeted towards Nintendo/Mario fans and casual gamers--the former is (hopefully) experienced and open-minded enough to know that the game can/will still be fun without Wi-Fi, and the latter, assuming they even know their Wii can go online (as I understand it, a surprising amount don't), likely won't be all that into online play. About the only group I can think of that might be alienated by Wi-Fi-less multiplayer would be guys that play lots of games online and just own a Wii as a console-on-the-side (and/or bought NSMB).