The most annoying video game sounds

[Alisbet]

What are the most annoying sounds you have encountered in a video game?

[Luigalaxy]

The baby crying sound effect from Yoshi's Island.

[Toad]

The low hearts sound from the Zelda series. I know I'm low on hearts but does the sound have to play to its own beat AND with EVERY swing of the sword?

[Weegee]

The low hearts sound from the Zelda series. I know I'm low on hearts but does the sound have to play to its own beat AND with EVERY swing of the sword?

Similarly, the low-HP alarm in Pokemon games. Three or four beeps when you first enter the red would suffice.

[Turtlekid1]

Don't forget the low-energy sound from Metroid titles, for that matter.

"YOU KNOW WHAT THEY SAY, THE MORE THE MERRIER!"

Most of the boss banter from the Kingdom Hearts series, but especially "GET UP ON THE HYDRA'S BACK!"

[Suber Bloober]

The noise the Mothership makes in the Atari 2600 game, E.T.

[Weegee]

All the dialogue in the 3D Sonic games, especially that in Shadow the Hedgehog.

[Turtlekid1]

Oh, come now.  "Where's that [darn] FOURTH Chaos Emerald!" is possibly the best video game quote ever.

[Jman]

Similarly, the low-HP alarm in Pokemon games. Three or four beeps when you first enter the red would suffice.

Oh man, seconded big time.  I turn the DS volume down all the way when my respective mon reaches that point.

[jdaster64]

The low HP sound in any game would probably suffice; Super Paper Mario's rather incessant iteration comes to mind.

[Turtlekid1]

As for the Pokemon thing, supposedly the "DANGER" warning alarm will be replace by faster-paced music in Black and White.  That's one thing they've definitely improved.

[penguinwizard]

Those flying bats in Thorntail Hollow in Star Fox Adventures (and other places in the game). They're called Bloops. This 15-second cutscene's all you need to know. It's bad enough that they swoop down on you from nowhere, but they always do that annoying cackle and they like flying almost out of reach of your staff. I think many SFA players were delighted when they became skilled enough to pick off these jerks from a distance with the fire blast upgrade. The problem? You usually don't notice these buggers until they're right on top of you!

[Ultima Shadow]

"YOU KNOW WHAT THEY SAY, THE MORE THE MERRIER!"

I still hear it when I sleep.

[Alisbet]

As for the Pokemon thing, supposedly the "DANGER" warning alarm will be replace by faster-paced music in Black and White.  That's one thing they've definitely improved.

I'm not too sure about that one.

[kirbyman]

Navi's "HEY" or "LOOK OUT" or "LISTEN" from OoT-- possibly the most annoying sounds of them all.

EDIT: I may have found a sound (or jingle-- whatever you want to call it) that might top the Navi.