I'm always very paranoid and unsure about using the likes of the Life Orb and the move Substitute, because I always think "why would I want to take HP away from my own 'mon?" Explosion doesn't worry me as much, because presumably by the time I use that one, it'll be a last resort.
Also, Weegee, I would say out of the choices you've got there, Energy Ball would be the best type for coverage purposes. But Grass Knot may be better (I don't know since that's another move I rarely use). Admittedly, I'm not terribly versed in competitive strategy.