You'd be right to think comedy is something games haven't really gotten their hooks into yet. But some really great examples do exist. Fighting in God Hand is hilarious, between the outrageous enemies and the moves you use on them. Especially the big payoff super moves--a few of them are all about the brutality, but most of them are satisfyingly funny. Dead Rising 1 and 2 are about using everyday items as improvised weapons on crowds of braindead people, and that on its own is comic gold. Banjo-Kazooie, quality dry humor throughout.
