It has been said many times that the Revolution may be Nintendo's last attempt at holding their ground in the console market. Satoru Iwata is even a bit nervous about system's success, stating that the Revolution would be a "complete failure" if it did not outsell the GameCube.
Nintendo is taking a big risk in developing their unique controller. They are trying a concept that no one has ever seen before in gaming, much like the DS's touch-screen feature, and are putting all their resources into making it a successful product.
Many of you may think of the Revolution as a rebirth of the NES era, where innovation and gameplay will once again reign supreme. This may actually work, if Nintendo manages to utilize the controller effectively. Many third-party developers have expressed interest in making games using the controller, but with a lack of actual game demos, nor an official list of developer support, it is best to take these comments with a grain of salt.
Remember when many developers wanted to support the GameCube, then they quickly backed out once they realized the system wasn't selling to anyone's expectations?
The same thing could happen with the Revolution. It could be the next flop like the Virtual Boy, or it could be a resounding success like the NES.
The only thing Nintendo has to do is gain enough thrid-party support and develop games that actually utilize the features of the Revolution's controller.