Just if you have an emulator with mario roms.
These are difficult to find(the emus and the roms), i tell you, and just exists nes and snes emulators, don't wait a psx or n64 emulator. I've got ZSNES and is pretty cool, you know.
Now you surely ask ¿Why no mario games on pc?
Well, make your own phrase:
mario nintendo of is exlusive